Teaching NeuroImages: Extrapontine osmotic demyelination in hypernatremia
نویسندگان
چکیده
منابع مشابه
Isolated extrapontine myelinolysis of osmotic demyelination syndrome.
The osmotic demyelination syndrome (ODS) has been identified as a complication of the rapid correction of hyponatremia for decades (King and Rosner, 2010). However, in recent years, a variety of other medical conditions have been associated with the development of ODS, independent of changes in serum sodium which cause a rapid changes in osmolality of the interstitial (extracellular) compartmen...
متن کاملCentral pontine and extrapontine myelinolysis: the osmotic demyelination syndromes.
Correspondence to: Dr R J Martin, Department of Neurology, Gloucestershire Royal Hospital, Great Western Road, Gloucester GL1 3NN, UK; roswell.martin@gloucr-tr. swest.nhs.uk _________________________ C entral pontine myelinolysis (CPM) was described by Adams and colleagues in 1959 as a disease affecting alcoholics and the malnourished. The concept was extended from 1962 with the recognition tha...
متن کاملA Case of Osmotic Demyelination Presenting with Severe Hypernatremia
Osmotic demyelination syndrome is a demyelinating disorder associated with rapid correction of hyponatremia. But, it rarely occurs in acute hypernatremia, and it leads to permanent neurologic symptoms and is associated with high mortality. A 44-year-old woman treated with alternative medicine was admitted with a history of drowsy mental status. Severe hypernatremia (197mEq/L) with hyperosmolali...
متن کاملExtrapontine Myelinolysis of Osmotic Demyelination Syndrome in a Case of Postoperative Suprasellar Arachnoid Cyst
The extrapontine myelinolysis of osmotic demyelination syndrome (ODS) is a well-known but uncommon disorder of the central nervous system. Although the mechanism is not fully understood and the treatment is controversial, hyponatremia is probably considered to be the main pathophysiological basis. There are few reports of ODS caused by a sellar lesion. Here we present a case of suprasellar arac...
متن کاملTeaching neuroimages: neuroradiologic findings in pontine and extrapontine myelinolysis: clue for the pathogenesis?
A 58-year-old woman presented with subacute onset of tetraparesis, anarthria, and dysphagia after rapid correction of hyponatremia caused by repeated vomiting. Brain MRI showed pontine and extrapontine lesions typical for the osmotic demyelination syndrome (figure, A and B). The pontine lesion showed nonhomogeneous contrast enhancement (figure, C), which diminished after 15 days (figure, D). Ba...
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ژورنال
عنوان ژورنال: Neurology
سال: 2020
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000009299